Modified constraint-induced movement therapy alters synaptic plasticity of rat contralateral hippocampus following middle cerebral artery occlusion
نویسندگان
چکیده
منابع مشابه
Dendritic plasticity in the adult rat following middle cerebral artery occlusion and Nogo-a neutralization.
Our work has shown that following focal ischemic lesion in adult rats, neutralization of the axon growth inhibitor Nogo-A with the monoclonal antibody (mAb) IN-1 results in functional recovery. Furthermore, new axonal connections were formed from the contralesional cortex to subcortical areas corresponding to the observed functional recovery. The present study investigated whether dendritic cha...
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Objective(s): Previous studies have indicated that phytoestrogens induce estrogenic as well as anti-inflammatory effects, and they are found in high abundance in the extracts of some herbs such as Vitex Agnus Castus (VAC). Therefore, we investigated the effect of VAC extract on ovariectomized mice after the induction of permanent middle cerebral artery occlusion (PMCAO...
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Background: Stroke is the third leading cause of death. Hypothermia has been recognized as an effective method in reducing brain injury. In this study, we assessed the effects of granulocyte colony-stimulating factor (G-CSF) as a neuroprotective agent and mild hypothermia on mortality, behavioral function, infarct volume, and brain edema in Wistar rats. Methods: Forty male rats were used in fiv...
متن کاملModified Constraint-induced Movement Therapy
Unilateral paralysis or paresis of an upper extremity can cause gross and fine motor functional impairments. These impairments can severely impact bilateral function of the upper extremities, thereby affecting a child’s participation in daily activities. Modified constraint-induced movement therapy (mCIMT) is an emerging and potentially effective treatment for children with unilateral upper ext...
متن کاملModified Constraint-induced Movement Therapy
Unilateral paralysis or paresis of an upper extremity can cause gross and fine motor functional impairments. These impairments can severely impact bilateral function of the upper extremities, thereby affecting a child’s participation in daily activities. Modified constraint-induced movement therapy (mCIMT) is an emerging and potentially effective treatment for children with unilateral upper ext...
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ژورنال
عنوان ژورنال: Neural Regeneration Research
سال: 2020
ISSN: 1673-5374
DOI: 10.4103/1673-5374.270312